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Physician-Supervised · GLP-1 Therapy · El Segundo, CA

GLP-1 Medical
Weight Loss in
El Segundo

Semaglutide and Tirzepatide programs with weekly in-office injections and full physician supervision. Serving Manhattan Beach, Hawthorne, Westchester, Playa Vista, and the LAX corridor.

📍 425 Main Street, El Segundo CA 90245 (424) 321‑4517 Mon–Wed, Fri–Sat
From $370 Semaglutide / 4 weeks
From $380 Tirzepatide / 4 weeks
$0 Consultation
Weekly In-Office Injections
GLP-1 Weight Loss at El Segundo

Physician-supervised weight loss — not a subscription service.

GLP-1 receptor agonists like Semaglutide and Tirzepatide support weight loss by regulating appetite, slowing gastric emptying, and improving insulin response. They are prescription medications — which means eligibility is determined by a licensed provider after a real in-person evaluation, not a questionnaire.

At our El Segundo location, every program includes weekly in-office injections, dose adjustments, side effect management, and ongoing provider oversight. You are not mailing yourself a box. You are working with a medical team.

Important: All online purchases are prepaid credits for consultation and potential treatment. If you are not a candidate after your evaluation, you receive a full refund or may apply the credit to another service.

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What Every Program Includes
In-person medical evaluation before any treatment begins
Weekly in-office injections with licensed provider oversight
Personalized dose titration based on your response and tolerance
Side effect support — nausea protocols, hydration, meal timing
Progress check-ins with dose adjustments throughout your plan
Nutrition and habit guidance aligned with your schedule
Financing: Klarna, Affirm, CareCredit — no large upfront costs required
Semaglutide El Segundo

Semaglutide Weight Loss

A GLP-1 receptor agonist that supports appetite regulation, slower gastric emptying, and improved insulin response. Wegovy® is FDA-approved for weight management. Your provider determines the appropriate formulation and dosing at your evaluation.

Semaglutide is a prescription medication. Treatment is provided only after an in-person medical evaluation confirming eligibility. Online purchases are prepaid credits for consultation and potential treatment — not a sale of medication. Medication sourcing and formulation are determined by your provider. If you are not a candidate, you will receive a full refund or may apply the credit to another service.

Starter
Starter Package
4 weekly doses · 0.25 mg → 0.5 mg titration
$370 / 4 weeks
$270 new patient offer · $100 off, one-time

Designed to begin appetite support with weekly oversight. Starts at 0.25 mg for two weeks, then 0.5 mg for the next two. Ideal for patients beginning their GLP-1 journey.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment.

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Step-Up Package
4 weekly doses · 0.5 mg/week
$390 / 4 weeks
$290 new patient offer · $100 off, one-time

For patients ready for steadier appetite control. Maintains 0.5 mg weekly with full medical supervision and ongoing check-ins.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Pro Package
4 weekly doses · 1.5 mg/week
$465 / 4 weeks
$365 new patient offer · $100 off, one-time

Stronger appetite support without large dose jumps. For patients medically cleared to advance from lower phases with weekly guidance included.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Advanced
Advanced Package
4 weekly doses · 2 mg/week
$565 / 4 weeks
$465 new patient offer · $100 off, one-time

For patients who have built tolerance and been medically cleared for higher dose support. Guided care and weekly check-ins included.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Max
Max Package
4 weekly doses · 2.5 mg/week
$665 / 4 weeks
$525 new patient offer · $100 off, one-time · $100 off, one-time

Highest dose range option for patients who have built tolerance and are medically appropriate. Weekly follow-ups throughout.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Not sure which package to start with?

Your provider determines the right dose and plan at your in-person evaluation.
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Tirzepatide El Segundo

Tirzepatide Weight Loss

A dual GIP and GLP-1 receptor agonist. Tirzepatide activates two hormone pathways simultaneously, which may produce greater weight loss results in some patients compared to GLP-1-only therapy. FDA-approved for type 2 diabetes; may be prescribed off-label for weight management when appropriate.

Tirzepatide is a prescription medication. Treatment is provided only after an in-person medical evaluation confirming eligibility. Online purchases are prepaid credits for consultation and potential treatment — not a sale of medication. Medication sourcing and formulation are determined by your provider. If you are not a candidate, you will receive a full refund or may apply the credit to another service.

Starter
Starter Package
4 weekly doses · 2.5 mg/week
$380 / 4 weeks
$280 new patient offer · $100 off, one-time

Introductory Tirzepatide phase at 2.5 mg weekly under full medical supervision. Designed to minimize side effects while beginning dual-hormone appetite regulation.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Step-Up Package
4 weekly doses · 5 mg/week
$465 / 4 weeks
$365 new patient offer · $100 off, one-time

For patients continuing from the starter phase under provider supervision. Increased appetite regulation with structured weekly support.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Pro Package
4 weekly doses · 10 mg/week
$625 / 4 weeks
$525 new patient offer · $100 off, one-time

For patients who have successfully completed earlier stages and been medically approved to advance. Ongoing supervision and weekly follow-ups.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Advanced
Advanced Package
4 weekly doses · 12.5 mg/week
$725 / 4 weeks
$625 new patient offer · $100 off, one-time

For patients approved to continue at higher doses after prior stages. Weekly monitoring and personalized care focused on long-term stability.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Max
Max Package
4 weekly doses · 15 mg/week
$825 / 4 weeks
$725 new patient offer · $100 off, one-time

Highest Tirzepatide dose for patients who have demonstrated tolerance and been medically approved. Maximum metabolic support with continuous professional monitoring.

Dosing may vary based on provider assessment. Online purchase is a prepaid credit for consultation and potential treatment. If you are not a candidate, you will receive a full refund or may apply the same credit to another eligible service.

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Semaglutide vs. Tirzepatide

Which GLP-1 Program Is Right for You?

Both are effective. Your provider will recommend the right one based on your health history, goals, and how your body responds. Here is how they differ.

Semaglutide Tirzepatide
MechanismGLP-1 receptor agonistDual GLP-1 + GIP receptor agonist
FDA approvalWegovy® for weight loss · Ozempic® for T2DMounjaro® for T2D · Off-label for weight management
Starting price$370 / 4 weeks$380 / 4 weeks
Injection frequencyOnce weeklyOnce weekly
Hormone pathwaysOne (GLP-1)Two (GLP-1 + GIP)
Good forMost patients · Strong GLP-1 evidence basePatients seeking dual-hormone approach · PCOS · Insulin resistance
Side effectsNausea, GI — typically temporarySimilar profile · Managed through titration

Your provider makes the final recommendation at your in-person evaluation based on your full health history.

Questions about which program is right for you?

Text us at (844) 759-6757 and a licensed provider will follow up directly.
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What to Expect

Timeline & Results

Your First Visit
Evaluation & Program Design

Your provider reviews your health history, current medications, goals, and any contraindications. If you are a candidate, you leave with a program plan, written pricing, and your first injection the same day.

Weeks 1–4
Foundation Phase

Weekly injections at starting dose. Most patients notice reduced appetite and smaller portions within the first two to three weeks. Your provider monitors tolerance and adjusts your plan as needed.

Weeks 5–12
Dose Progression

Dose is adjusted upward based on your response and tolerance. Body composition changes typically become more visible. Nutrition and hydration guidance reinforced at check-ins.

Months 3–6+
Sustained Progress & Maintenance

Most patients see meaningful results in this window. Your provider stabilizes you at the dose that balances results and comfort. Exit planning and lifestyle guidance support long-term consistency.

Good Candidates
Adults with a BMI of 30+ or 27+ with weight-related conditions
No contraindications to GLP-1 therapy (discussed at evaluation)
PCOS, insulin resistance, or pre-diabetic conditions
Willing to pair treatment with healthy nutrition and activity
Committed to weekly visits and ongoing medical oversight
A note on results

Individual results vary significantly. Factors including starting weight, metabolism, diet, activity level, and consistency all affect outcomes. Your provider will set realistic expectations based on your specific situation — not population averages.

FAQ

Common Questions

What is the difference between Semaglutide and Tirzepatide?

Semaglutide activates GLP-1 receptors, which regulate appetite and insulin response. Tirzepatide activates both GLP-1 and GIP receptors — a dual-hormone approach that may produce greater weight loss in some patients. Both require a prescription and in-person evaluation. Your provider will recommend the right option based on your health history and goals.

What does the dual GIP + GLP-1 mechanism in Tirzepatide do differently?

GIP complements GLP-1 by improving glucose-dependent insulin release and promoting fat metabolism. Together, the two pathways may provide stronger appetite control and better metabolic outcomes than GLP-1 activation alone — particularly for patients with insulin resistance, PCOS, or metabolic syndrome.

When will I see results?

Many patients notice reduced appetite and smaller portions within the first two to three weeks. Visible body composition changes typically develop over three to six months of consistent treatment. Results vary by individual — your provider will set realistic expectations based on your starting point.

What are the side effects?

The most common side effects are gastrointestinal — nausea, mild diarrhea, or constipation — and are typically most noticeable in the early weeks as your body adjusts to the medication. They generally improve with dose titration, meal timing adjustments, and hydration. Your provider manages side effects throughout your program.

Is this available at your El Segundo location?

Yes. Both Semaglutide and Tirzepatide programs are available at our El Segundo suite at 425 Main Street. Your evaluation, weekly injections, and all check-ins take place in-office. We serve Manhattan Beach, Hawthorne, Westchester, Playa Vista, Inglewood, and the LAX corridor.

Will I lose muscle along with fat?

Unlike crash diets or stimulant-based plans, GLP-1 therapy primarily targets fat. When paired with adequate protein intake and light resistance training, most patients preserve or improve lean body mass. Your provider will advise on nutrition and activity as part of your program.

What happens when I stop the medication?

If stopped without lifestyle support in place, appetite and weight may rebound. That is why our program includes exit planning, nutrition guidance, and strategies to maintain results after discontinuation. Your provider will work with you on a responsible transition when the time comes.

Can these be combined with other treatments?

Yes. Depending on your goals and medical history, GLP-1 therapy may complement other services including peptide therapy, body contouring, or skin tightening. Your provider will advise on timing and compatibility at your evaluation.

Do you offer financing?

Yes — Klarna, Affirm, and CareCredit are all accepted at El Segundo. Text PLAN to (844) 759-6757 and we will walk you through installment options.

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Why Skin Works

The Skin Works Difference

👩‍⚕️
Real Medical Oversight
Every program supervised by a licensed provider. In-person evaluation before any treatment begins — not a questionnaire.
💉
Weekly In-Office Injections
You come in weekly. Your provider monitors your response, adjusts your dose, and manages side effects in real time.
1,500+ Reviews · 4.9★
Consistent results and documented care across Google and Yelp from real patients in the South Bay.
💳
Flexible Financing
Klarna, Affirm, and CareCredit accepted. Monthly options so you can stay consistent without large upfront costs.

Find Us in
El Segundo

Address

425 Main Street
El Segundo, CA 90245

Between Manhattan Beach and LAX

Hours

Mon–Wed, Fri–Sat · By appointment only
No walk-ins

Contact

(424) 321-4517 · Text (844) 759-6757

Nearby

5–10 min: Manhattan Beach, LAX, Westchester
10–15 min: Hawthorne, Inglewood, Playa Vista
15 min: Marina del Rey, Lawndale

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Information on this page is for educational purposes only and is not a substitute for medical advice. Semaglutide and Tirzepatide are prescription medications. Treatment is provided only after an in-person medical evaluation by a licensed provider who confirms clinical appropriateness. Online purchases are prepaid credits for consultation and potential treatment — not a sale of medication. Individual results vary. Ozempic® and Wegovy® are registered trademarks of Novo Nordisk. Mounjaro® is a registered trademark of Eli Lilly. Skin Works Medical Spa does not sell or dispense brand-name Ozempic®, Wegovy®, or Mounjaro® through online checkout.

El Segundo · 425 Main Street · GLP-1 Weight Loss

Ready to Start Your Program?

Semaglutide and Tirzepatide programs at our El Segundo location. Text us at (844) 759-6757 with any questions — a licensed provider will follow up directly.

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💬 Or text us at (844) 759-6757